The Lions will host the Bills in the opening Thanksgiving game at 12:30 pm EST. The Bills were a 10-point favorite as of Tuesday night, and the total was set at 54 points.
The Bills are the betting favorite to win the Super Bowl this season, but the Lions have won three straight games outright as an underdog. Both teams are also cooking offensively, ranking in the top 11 in total offense, passing, rushing, and scoring.
While I believe the Bills will get more stops than the Lions, 10 points is a lot to lay against a surging team on their home turf. My favorite play for this game is over 54.

America’s team will host the Giants during the heart of the day. The Cowboys are a 9.5-point favorite, with the total set at 45.5. Although the spread is large, the Cowboys did beat the Giants earlier this season on the road by seven without Dak Prescot. The Giants also have a long list of injuries that continue to pile up since Sunday’s loss to Detroit. One thing about the Cowboys is when they win, they have won big lately, with their last five wins coming by 12 points or more. I’d either lay the 9.5 on the Boys for this game or pass. But I can’t trust New York in this spot.

For the NFL nightcap, we have the Minnesota Vikings, who are coming off an embarrassing 40-3 home loss, hosting the New England Patriots, who are on a three-game winning streak and have won five of their last six games. With the Vikings sitting as a 2.5-point favorite and the total set at 42.5, this is expected to be the closest game on the turkey day slate.

On the college side, there’s the Egg Bowl between the Ole Miss Rebels and the Mississippi State Bulldogs. Ole Miss is a two-point home favorite, and the total is set at 59. The Rebels beat the Bulldogs as a 2.5-point road underdog last season.
A big story around this game involves rumors that Lane Kiffin is in talks with Auburn to become their next head coach. Will the rumors have any effect on the Ole Miss players? Soon we shall see.
Let me know which Thanksgiving game you are most excited to watch and what is your favorite personal bet for the day.